SCRIB antibody (C-Term)

Catalog No. ABIN190696

Product Details anti-SCRIB Antibody

Target: SCRIB (Scribbled Homolog (SCRIB))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCRIB antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Not reactive in: no confirmed exceptions from predicted reactivity known in the moment

Predicted Reactivity: human

Characteristics: Expected / apparent Molecular Weight of the Antigene: 175 kDa

Purification: serum

Immunogen: GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains

Application Details

Application Notes: 1: 5 000 with standard ECL (WB)

Comment:

reactivity showed on dilluted human cell culture extracts

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μL of sterile water

Handling Advice: Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Target Details for SCRIB

Target: SCRIB (Scribbled Homolog (SCRIB))

Alternative Name: hScrib (SCRIB Products)

Synonyms: 0424/05 antibody, CG31082 antibody, CG42614 antibody, CG43398 antibody, CG5462 antibody, CG5467 antibody, CT17324 antibody, Dmel\\CG43398 antibody, Dmel_CG31082 antibody, Dmel_CG42614 antibody, Dmel_CG5462 antibody, Dmel_CG5467 antibody, MENE (3R)-F antibody, SCR antibody, Scb antibody, Scrb antibody, Scrib antibody, ird antibody, ird15 antibody, l(3)673 antibody, l(3)S042405 antibody, l(3)c00119 antibody, l(3)j7B3 antibody, scrb antibody, smi97B antibody, vart antibody, AI118201 antibody, CRIB antibody, Crc antibody, SCRIB1 antibody, Scrb1 antibody, mKIAA0147 antibody, vartul antibody, scrb1 antibody, scribble antibody, scribble1 antibody, si:ch211-12p8.1 antibody, si:zc12p8.1 antibody, CRIB1 antibody, SCRB1 antibody, Vartul antibody, scribbled antibody, scribbled planar cell polarity antibody, scribbled planar cell polarity protein antibody, scrib antibody, Scrib antibody, SCRIB antibody

Background: Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4

Molecular Weight: 175 kDa

UniProt: Q14160

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization