IL-1 beta antibody

Catalog No. ABIN191246

There are 2+ publications for this product available. The Mouse Monoclonal anti-IL-1 beta antibody is suitable to detect IL-1 beta in samples from Human. It has been validated for ELISA and ELISA (Capture).

Quick Overview for IL-1 beta antibody (ABIN191246)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: ELISA, ELISA (Capture)

Clone: 1E6

Product Details anti-IL-1 beta Antibody

Specificity: MAbs react with three different determinants on IL-1, β molecule. MAbs do not inhibit the biological activity of IL-1. IgG2a for MAb 6E10 IgG2b for MAb 11E5 IgM for MAb 5C10

Cross-Reactivity: Human

Purification: Purified

Isotype: IgG2b

Application Details

Application Notes: Detection of IL-1, β in two-site immunoassay. We recommend using mixture of MAbs 6E10 and 11E5 for coating and MAb 5C10 for labeling. Detection of IL-1, β in immunohistochemistry.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4, 0.1 % sodium azide (NaN3) Material safety note: This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1 %) as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-IL-1 beta antibody (ABIN191246)

Rikimaru, Awano, Mineoka, Yoshida, Ansai, Takehara: "Relationship between endothelin-1 and interleukin-1beta in inflamed periodontal tissues." in: Biomedical research (Tokyo, Japan), Vol. 30, Issue 6, pp. 349-55, (2010) (PubMed).

Zavialov, Batchikova, Korpela, Petrovskaya, Korobko, Kersley, MacIntyre, Zavyalov: "Secretion of recombinant proteins via the chaperone/usher pathway in Escherichia coli." in: Applied and environmental microbiology, Vol. 67, Issue 4, pp. 1805-14, (2001) (PubMed).

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: Interleukin-1 beta / IL-1B

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome