TIAM2 antibody (AA 9-19)

Catalog No. ABIN1941852

Product Details anti-TIAM2 Antibody

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Binding Specificity: AA 9-19

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This TIAM2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human TIAM2. This antibody is expected to recognize isoform a (NP_036586.2) only.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide TLQGSKNHSNT-C from the N-terminus of human TIAM2 (NP_036586.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Panda (100%), Mouse, Bovine, Elephant, Horse, Guinea pig (91%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:64000)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Preliminary experiments gave bands at approx 150kD and 37kD in Mouse and Rat Brain lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 192kD according to mouse NP_036008.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TIAM2

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Alternative Name: TIAM2 (TIAM2 Products)

Synonyms: STEF antibody, TIAM-2 antibody, 3000002F19Rik antibody, mKIAA2016 antibody, TIAM2 antibody, T-cell lymphoma invasion and metastasis 2 antibody, T cell lymphoma invasion and metastasis 2 antibody, T-cell lymphoma invasion and metastasis 2a antibody, T-lymphoma invasion and metastasis-inducing protein 2 antibody, TIAM2 antibody, Tiam2 antibody, tiam2a antibody, LOC100598161 antibody

Background: Name/Gene ID: TIAM2

Synonyms: TIAM2, KIAA2016, STEF, TIAM-2

Gene ID: 26230

NCBI Accession: NP_036586

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha