HLAG antibody

Catalog No. ABIN1959962

The Mouse Monoclonal anti-HLAG antibody is suitable to detect HLAG in samples from Human. It has been validated for ELISA, FACS, IHC, IHC (fro), Func, BR, Inhibition and Neut.

Quick Overview for HLAG antibody (ABIN1959962)

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLAG antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Blocking Reagent (BR), Blocking Antibody (Inhibition), Neutralization (Neut)

Clone: 87G

Product Details anti-HLAG Antibody

Specificity: Monoclonal antibody 87G recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1 and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells. The antibody 87G blocks interaction of HLA-G with inhibitory receptors.

Purification: Protein A purified

Immunogen: H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.

Isotype: IgG2a

Application Details

Application Notes: Approved: Block, ELISA, Flo, Func, IHC, IHC-Fr, Inhb, Neut

Usage: Flow Cytometry: Recommended dilution - 2 μg/mL. Positive control - JEG-3 human choriocarcinoma epithelial cell line. Immunohistochemistry (frozen sections): Recommended dilution - 10 μg/mL. Incubation: 20 min at 25 degrees C. Positive tissue - extravillou

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for HLAG

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Alternative Name: HLA-G

Background: Name/Gene ID: HLA-G

Synonyms: HLA-G, HLAG, HLA-6.0, MHC class I antigen G, HLA G antigen

Gene ID: 3135

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response