GRIA2 antibody (Ser880)
Quick Overview for GRIA2 antibody (Ser880) (ABIN197558)
Target
See all GRIA2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Ser880
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Specificity
- Glutamate receptor 2 (Precursor) antibody detects endogenous levels of total Glutamate receptor 2(Precursor) protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human Glutamate receptor 2(Precursor) around the phosphorylation site of serine 880 (I-E- SP-V-K).
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Application Notes
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Western Blot: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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Alternative Name
- Glutamate Receptor 2 / GLUR2
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Background
- Glutamate receptors sensitive to AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate) are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. These channels are assembled from 4 related subunits, GLURA (GRIA1), GLURB (GRIA2), GLURC (GRIA3), GLURD (GRIA4), with the GLURB subunit rendering the channel almost impermeable to Ca(2+).Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic
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Gene ID
- 2891
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NCBI Accession
- NP_000817
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UniProt
- P42262
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Pathways
- PI3K-Akt Signaling
Target
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