CD42a antibody

Catalog No. ABIN198676

Product Details anti-CD42a Antibody

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD42a antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody belongs to CD42a (assigned at the Fourth International Workshop on Leukocyte Differentiation Antigens, Vienna, 1989)1 and binds to the 22000 dalton IX subunit of the glycoprotein Ib-IX complex. Failed to bind to platelets from patients with Bernard-Soulier Syndrome. Cell reactivity: The antibody is specific for cells of the platelet megakaryocyte lineage. It reacts with a proportion of acute myeloid leukemias being useful in identifying those of the megakaryoblastic subtype.

Purification: Purified

Immunogen: Peripheral blood mononuclear cells isolated on Ficoll Hypaque.

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, IHC, IHC-Fr

Usage: Suitable for enumeration of platelets by flow cytometry and immunoperoxidase staining of frozen tissue sections or air dried smear preparations7, and for identification of megakaryoblasts in acute myeloid leukemia or acute myelofibrosis.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 25 mM Tris-HCl, 0.4 M sodium chloride,  pH 8.0, 0.2 % BSA, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD42a

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Alternative Name: GP9 / CD42a (GP9 Products)

Synonyms: cd42a antibody, gpix antibody, GP9 antibody, GPIX antibody, Cd42 antibody, CD42a antibody, glycoprotein IX platelet antibody, glycoprotein IX platelet L homeolog antibody, glycoprotein IX (platelet) antibody, glycoprotein 9 (platelet) antibody, GP9 antibody, gp9.L antibody, Gp9 antibody

Background: Name/Gene ID: GP9

Synonyms: GP9, CD42a, GPIX, Glycoprotein 9, Glycoprotein IX (platelet), GP-IX, CD42a antigen, gp9, Platelet glycoprotein IX

Gene ID: 2815

UniProt: P14770