PZP antibody (AA 472-821) (Biotin)

Catalog No. ABIN1993627

Product Details anti-PZP Antibody (Biotin)

Target: PZP (Pregnancy Zone Protein (PZP))

Binding Specificity: AA 472-821

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PZP antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Pregnancy zone protein (472-821AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PZP

Target: PZP (Pregnancy Zone Protein (PZP))

Alternative Name: PZP (PZP Products)

Synonyms: A1m antibody, pregnancy zone protein antibody, pregnancy-zone protein antibody, CpipJ_CPIJ000348 antibody, Pzp antibody, PZP antibody

Background:

Background: Is able to inhibit all four classes of proteinases by a unique \\\'trapping\\\' mechanism. This protein has a peptide stretch, called the \\\'bait region\\\' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Aliases: PZP antibody, CPAMD6 antibody, Pregnancy zone protein antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6 antibody

UniProt: P20742