BAFF antibody (AA 68-285)
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- Target See all BAFF (TNFSF13B) Antibodies
- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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Binding Specificity
- AA 68-285
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BAFF antibody is un-conjugated
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (68-285AA)
- Isotype
- IgG
- Top Product
- Discover our top product TNFSF13B Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
- Alternative Name
- TNFSF13B (TNFSF13B Products)
- Synonyms
- BAFF antibody, BLYS antibody, CD257 antibody, DTL antibody, TALL-1 antibody, TALL1 antibody, THANK antibody, TNFSF20 antibody, ZTNF4 antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, TNFSF13B antibody, RGD1561519 antibody, RGD1560810 antibody, BLyS antibody, D8Ertd387e antibody, zTNF4 antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, zgc:172115 antibody, TNF superfamily member 13b antibody, TNF receptor superfamily member 13C antibody, tumor necrosis factor (ligand) superfamily, member 13b antibody, tumor necrosis factor receptor superfamily, member 13c antibody, tumor necrosis factor superfamily member 13b antibody, TNFSF13B antibody, TNFRSF13C antibody, Tnfsf13b antibody, Tnfrsf13c antibody, tnfsf13b antibody
- Background
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Background: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Isoform 3:Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly regulate the differential expression of a large number of genes involved in the innate immune response and the regulation of apoptosis.
Aliases: ApoL related ligand TALL 1 antibody, B cell Activating Factor antibody, B lymphocyte stimulator antibody, B-cell-activating factor antibody, BAFF antibody, BLyS antibody, CD 257 antibody, CD257 antibody, CD257 antigen antibody, Delta BAFF antibody, Dendritic cell derived TNF like molecule antibody, Dendritic cell-derived TNF-like molecule antibody, DTL antibody, DTL precursor antibody, PRO738 antibody, soluble form antibody, TALL 1 antibody, TALL-1 antibody, TALL1 antibody, THANK antibody, TN13B_HUMAN antibody, TNF and APOL related leukocyte expressed ligand 1 antibody, TNF homolog that activates apoptosis antibody, TNF homolog that activates apoptosis NKFB and JNK. antibody, TNF- and APOL-related leukocyte expressed ligand 1 antibody, TNFSF13B antibody, TNFSF20 antibody, TNLG7A antibody, Tumor necrosis factor (ligand) superfamily member 13b antibody, Tumor necrosis factor ligand 7A antibody, Tumor necrosis factor ligand superfamily member 13b antibody, Tumor necrosis factor ligand superfamily member 20 antibody, Tumor necrosis factor like protein ZTNF4 antibody, Tumor necrosis factor superfamily member 13B antibody, UNQ401 antibody, ZTNF4 antibody
- UniProt
- Q9Y275
- Pathways
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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