UBE2V2 antibody (AA 2-145) (HRP)

Catalog No. ABIN1994539

Product Details anti-UBE2V2 Antibody (HRP)

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Binding Specificity: AA 2-145

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2V2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-conjugating enzyme E2 variant 2 protein (2-145AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBE2V2

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Alternative Name: UBE2V2 (UBE2V2 Products)

Synonyms: DDVIT1 antibody, DDVit-1 antibody, EDAF-1 antibody, EDPF-1 antibody, EDPF1 antibody, MMS2 antibody, UEV-2 antibody, UEV2 antibody, mms2 antibody, uev2 antibody, edpf1 antibody, uev-2 antibody, ddvit1 antibody, edaf-1 antibody, edpf-1 antibody, ddvit-1 antibody, 1110021H13Rik antibody, 4632410D19Rik antibody, 5730524P06Rik antibody, 6820402M05 antibody, AI848315 antibody, C81524 antibody, wu:fb18b11 antibody, wu:fb24d11 antibody, zgc:63717 antibody, UBE2V2 antibody, TMEM189-UBE2V1 antibody, ubiquitin conjugating enzyme E2 V2 antibody, ubiquitin-conjugating enzyme E2 variant 2 antibody, ubiquitin conjugating enzyme E2 V2 S homeolog antibody, Ubiquitin-conjugating enzyme E2 variant 2 antibody, UBE2V2 antibody, Ube2v2 antibody, ube2v2 antibody, ube2v2.S antibody, PTRG_00824 antibody, ub2v2 antibody, Tsp_08004 antibody

Background:

Background: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through \'Lys-63\'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Aliases: 1 alpha 25 dihydroxyvitamin D3 inducible antibody, DDVit 1 antibody, DDVIT1 antibody, EDAF-1 antibody, EDAF1 antibody, EDPF-1 antibody, EDPF1 antibody, Enterocyte differentiation associated factor EDAF 1 antibody, Enterocyte differentiation promoting factor antibody, Enterocyte differentiation-associated factor 1 antibody, Enterocyte differentiation-promoting factor 1 antibody, Methyl methanesulfonate sensitive 2 antibody, MMS 2 antibody, MMS2 antibody, MMS2 homolog antibody, UB2V2_HUMAN antibody, UBE2V 2 antibody, UBE2V2 antibody, Ubiquitin conjugating enzyme E2 variant 2 antibody, Ubiquitin conjugating enzyme E2v2 antibody, Ubiquitin-conjugating enzyme E2 variant 2 antibody, UEV 2 antibody, UEV2 antibody, Vitamin D3 inducible protein antibody, Vitamin D3-inducible protein antibody

UniProt: Q15819

Pathways: Positive Regulation of Response to DNA Damage Stimulus