FANCE antibody (AA 1-13)

Catalog No. ABIN199966

Product Details anti-FANCE Antibody

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Binding Specificity: AA 1-13

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCE antibody is un-conjugated

Application: ELISA

Specificity: Amino acids 1-13 of Human FANCE. This Fanconi anemia protein promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage. LocusLink ID 2178, SwissProt accession number Q9HB96.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from human FANCE.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA

Usage: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride,  pH 7.2, 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid cycles of freezing and thawing.

Storage: -20 °C

Storage Comment: Store vial at -20°C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid freeze-thaw cycles.

Target Details for FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Alternative Name: FANCE (FANCE Products)

Synonyms: FANCE antibody, fae antibody, face antibody, FACE antibody, FAE antibody, 2810451D06Rik antibody, AI415634 antibody, AW209126 antibody, RGD1561045 antibody, Fanconi anemia complementation group E antibody, Fanconi anemia, complementation group E antibody, FANCE antibody, fance antibody, Fance antibody

Background: Name/Gene ID: FANCE

Synonyms: FANCE, FAE, Fanconi anemia group E protein, FACE, Protein FACE

Gene ID: 2178

UniProt: Q9HB96

Pathways: DNA Damage Repair