Insulin Receptor antibody

Catalog No. ABIN201098

The Mouse Monoclonal anti-Insulin Receptor antibody is suitable to detect Insulin Receptor in samples from Human, Cow, Rabbit, Pig and Sheep. It has been validated for Inhibition.

Quick Overview for Insulin Receptor antibody (ABIN201098)

Target: Insulin Receptor (INSR)

Reactivity: Human, Cow, Rabbit, Pig, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This Insulin Receptor antibody is un-conjugated

Application: Blocking Antibody (Inhibition)

Product Details anti-Insulin Receptor Antibody

Specificity: Recognizes a protein of 135kD, identified as the alpha subunit of human insulin receptor (IR). Its epitope localizes in exon 7/8 and shows no cross-reactivity with IGF-receptors. Species cross-reactivity: Human, bovine, porcine and sheep. Weakly reacts with rabbit. Does not react with mouse or rat.

Purification: Protein G purified

Immunogen: IM-9 lymphocytes followed by purified insulin receptor.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Inhb

Usage: Suitable for use in inhibiting insulin binding. Use antibody at 10nM.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for Insulin Receptor

Target: Insulin Receptor (INSR)

Alternative Name: INSR / Insulin Receptor

Background: Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase

Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

Gene ID: 3643

UniProt: P06213

Pathways: NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity