Integrin alpha 1 antibody

Catalog No. ABIN204310

Product Details anti-Integrin alpha 1 Antibody

Target: Integrin alpha 1 (ITGA1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin alpha 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Specificity: Recognizes the L domain (Val151-Ala364) of human alpha1 integrin (CD49a). Precipitates proteins of Mr 180kD, pI 5.9-6.0 (alpha chain) and Mr 115kD, pI 4.5-5.0 (beta chain) from human lymphocyte lysates. Does not recognize rat recombinant I domain of integrin alpha1.

Purification: Protein A purified

Immunogen:

Type of Immunogen: Native protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA (0.5 μg/mL), Flo (2 μg/mL), Func (1 - 5 μg/mL), IHC (2 μg/mL), IP (1 μg/mL), WB (2 μg/mL)

Usage: Suitable for use in ELISA, Immunohistochemistry, Western Blot, Immunoprecipitation, Flow Cytometry and Inhibition of activated human lymphocyte binding to laminin, collagen IV and fibronectin. Immunohistochemistry: 2 μg/mL, with paraformaldehyde fixation. Western Blot: 2 μg/mL. Immunoprecipitation: 1 μg/mL. Flow Cytometry: 2 μg/mL. ELISA: 0.5 μg/mL. Inhibition: 1-5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01 M PBS,  pH 7.1, 0.15 M sodium chloride, no preservatives.

Preservative: Without preservative

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: ITGA1/CD49a/Integrin Alpha 1 (ITGA1 Products)

Synonyms: CD49A antibody, E130012M19Rik antibody, Vla1 antibody, CD49a antibody, VLA1 antibody, integrin alpha 1 antibody, integrin subunit alpha 1 antibody, Itga1 antibody, ITGA1 antibody

Background: Name/Gene ID: ITGA1
Family: Integrin

Synonyms: ITGA1, CD49a antigen, CD49a, Integrin Alpha 1, Integrin, alpha 1, Integrin alpha-1, Laminin and collagen receptor, Very late activation protein 1, VLA1, VLA-1

Gene ID: 3672

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex