Insulin antibody

Catalog No. ABIN206973

The Mouse Monoclonal anti-Insulin antibody (Clone IN-05) (ABIN206973) specifically detects Insulin in IHC, ELISA, IHC (p), ICC, RIA, Func, Neut and BR. The antibody is reactive with Human, Pig and Cow samples.

Quick Overview for Insulin antibody (ABIN206973)

Target: Insulin (INS)

Reactivity: Human, Pig, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Insulin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Radioimmunoassay (RIA), Functional Studies (Func), Neutralization (Neut), Blocking Reagent (BR)

Clone: IN-05

Product Details anti-Insulin Antibody

Specificity: Reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas, it is also present in tumors of B cell origin such as insulinoma

Purification: Protein A purified

Immunogen: Porcine insulin.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: Block, ELISA, Func, ICC, IHC, IHC-P, Neut, RIA

Usage: Functional Application: The antibody IN-05 blocks binding of insulin to the receptor.

Comment:

Target Species of Antibody: Pig

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for Insulin

Target: Insulin (INS)

Alternative Name: Insulin

Background: Name/Gene ID: INS
Family: Hormone

Synonyms: INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin

Gene ID: 3630

UniProt: P01308

Pathways: NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation