HSP90AA1 antibody (AA 604-697)

Catalog No. ABIN6796592

Product Details anti-HSP90AA1 Antibody

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Binding Specificity: AA 604-697

Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Chicken, Cow, Guinea Pig, Pig, Sheep, Dog, Hamster, Water Mold, C. elegans

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP90AA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: Identifies purified bovine and human (alpha and beta) Hsp90 and detects a 90kD protein, corresponding to the apparent molecular mass of Hsp90 on SDS-PAGE immunoblots, in samples from human, mouse, rat, beluga, bovine, canine, C. elegans, chicken, fish (brook trout, carp, chinook salmon, chum salmon, medaka, rainbow trout), guinea pig, hamster, lobster, monkey, mussel, porcine, rabbit, scallop, sheep and water mold. Reacts with rodent glucocorticoid receptor, 95kD. Also reacts with proteins called proliferation potential proteins (P2PS), ~30-40kD. These proteins are associated with the 30-40S substructures of nuclear hnRNP complexes and they share an epitope in common with Hsp90. The epitope has been mapped to amino acids 604-697 of the human Hsp90 sequence. Detects both Hsp90 alpha and beta.

Purification: Protein G purified

Immunogen: Achlya ambisexualis (water mold) Hsp90.

Isotype: IgG1

Application Details

Application Notes: Approved: ICC, WB

Usage: Suitable for use in Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry and FACS. Western Blot (Colorimetric): 1 μg/mL. Immunoprecipitation: 4 μg/mL. Does not appear to react well with Hsp90 that is bound to steroid receptors or to pp60v-src of Rouse sarcoma virus. Positive control: Hsp90 (Human) Protein and HeLa (Heat Shocked) Cell Lysate.

Comment:

Target Species of Antibody: Achlya ambisexualis

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM PBS,  pH 7.2, 0.1 mM PMSF, 50 % glycerol.

Preservative: PMSF

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for HSP90AA1

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Alternative Name: HSP90AA1 / Hsp90 Alpha A1 (HSP90AA1 Products)

Synonyms: EL52 antibody, HSP86 antibody, HSP89A antibody, HSP90A antibody, HSP90N antibody, HSPC1 antibody, HSPCA antibody, HSPCAL1 antibody, HSPCAL4 antibody, HSPN antibody, Hsp89 antibody, Hsp90 antibody, LAP2 antibody, Hsp86 antibody, Hspca antibody, htpG antibody, 86kDa antibody, 89kDa antibody, AL024080 antibody, AL024147 antibody, Hsp86-1 antibody, hsp4 antibody, HSP90 antibody, HSP90AA1 antibody, fb17b01 antibody, hsp90 antibody, hsp90a antibody, hsp90a.1 antibody, hsp90alpha antibody, wu:fb17b01 antibody, zgc:86652 antibody, Hsp90alpha antibody, heat shock protein 90 alpha family class A member 1 antibody, heat shock protein 90, alpha (cytosolic), class A member 1 antibody, Heat Shock Protein 90, cytosolic antibody, heat shock protein 90A antibody, molecular chaperone antibody, heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 antibody, heat shock protein HSP 90-alpha antibody, heat shock protein 90kDa alpha (cytosolic), class A member 1 antibody, HSP90AA1 antibody, Hsp90aa1 antibody, HSP90A antibody, hsp90A antibody, hsp90aa1.1 antibody, LOC108698781 antibody

Background: Name/Gene ID: HSP90AA1

Synonyms: HSP90AA1, EL52, HSP86, Hsp89, HSP89A, HSPC1, Heat shock 86 kDa, Hsp90, HSP90A, HSP90N, HSPCA, HSPCAL4, HSPN, LAP2, HSP 86, HSPCAL1

Gene ID: 3320

UniProt: P07900

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals