alpha Estradiol antibody (Alexa Fluor 350)

Catalog No. ABIN2170082

Product Details

Target: alpha Estradiol

Host: Mouse

Clonality: Monoclonal

Conjugate: Alexa Fluor 350

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity (Details): alpha Estradiol

Purification: Purified by Protein G.

Immunogen: KLH conjugated alpha Estradiol

Clone: 2G2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: alpha Estradiol

Target Type: Hormone

Background:

Synonyms: 1,3,510-Estratriene-3,17alpha-diol, 3,17 alpha-Dihydroxy-1,3,510-estratriene, Epiestradiol, alpha Estradiol, 17 alpha Estradiol, Ethynyl Estradiol, Oestradiol, Estradial, Ovocylin.

Background: Estradiol (known as alpha Estradiol or 17 alpha Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture.17-estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer?s disease and ischemic stroke.