Collagen Type I antibody (AA 1051-1150)

Catalog No. ABIN2173309

This Rabbit Polyclonal antibody specifically detects Collagen Type I in WB, IF, IHC (fro), IHC (p), ICC and FACS. It exhibits reactivity toward Human. It has been mentioned in 12+ publications

Quick Overview for Collagen Type I antibody (AA 1051-1150) (ABIN2173309)

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Collagen Type I antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-Collagen Type I Antibody

Binding Specificity: AA 1051-1150

Purpose: Collagen I Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Collagen I

Isotype: IgG

Application Details

Application Notes: WB(1:200-1000), IHC-P(1:200-1000), IHC-F(1:200-1000), IF(1:200-1000), Flow-Cyt(1:50-100), ICC/IF(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Collagen Type I antibody (ABIN2173309)

Velázquez, Enos, Carson, Cranford, Bader, Sougiannis, Pritchett, Fan, Carson, Murphy: "miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice." in: Physiological reports, Vol. 5, Issue 18, (2018) (PubMed).

Li, Xiong, Gong: "Lyn kinase enhanced hepatic fibrosis by modulating the activation of hepatic stellate cells." in: American journal of translational research, Vol. 9, Issue 6, pp. 2865-2877, (2017) (PubMed).

Miyauchi, Yasuchika, Fukumitsu, Ishii, Ogiso, Minami, Kojima, Yamaoka, Katayama, Kawai, Yoshitoshi-Uebayashi, Kita, Yasuda, Sasaki, Uemoto: "A novel three-dimensional culture system maintaining the physiological extracellular matrix of fibrotic model livers accelerates progression of hepatocellular carcinoma cells." in: Scientific reports, Vol. 7, Issue 1, pp. 9827, (2017) (PubMed).

Zhang, Dang, Li, Hao, Li, Qi: "Cardiac Contractility Modulation Attenuate Myocardial Fibrosis by Inhibiting TGF-β1/Smad3 Signaling Pathway in a Rabbit Model of Chronic Heart Failure." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 1, pp. 294-302, (2017) (PubMed).

Zhou, Zhu, Zhang, Zhang, Zhou, Wang, He: "Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling." in: Experimental and therapeutic medicine, Vol. 11, Issue 5, pp. 1748-1754, (2016) (PubMed).

Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, (2016) (PubMed).

Jiang, Chun, Wang, Du, Wang, Xiong: "Effect of transforming growth factor-β3 on the expression of Smad3 and Smad7 in tenocytes." in: Molecular medicine reports, Vol. 13, Issue 4, pp. 3567-73, (2016) (PubMed).

Liang, Li, Wang, Chen, Zhao, Sun, Zhuang, Shi, Shen, Zhang, Dai: "A collagen-binding EGFR antibody fragment targeting tumors with a collagen-rich extracellular matrix." in: Scientific reports, Vol. 6, pp. 18205, (2016) (PubMed).

Lu, Wang, Zhang, Zhou, Zuo, You, Gao, Liu, Tang: "A novel silk fibroin nanofibrous membrane for guided bone regeneration: a study in rat calvarial defects." in: American journal of translational research, Vol. 7, Issue 11, pp. 2244-53, (2016) (PubMed).

Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, (2015) (PubMed).

Luo, Zhang, Wang, Hu, Song, Zhang: "The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model." in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, (2014) (PubMed).

Target Details for Collagen Type I

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Alternative Name: Collagen I

Background: Synonyms: Collagen type I, alpha 1 type I collagen, alpha 2 type I collagen, COL1A1, COL1A2, Collagen I alpha 1 polypeptide, Collagen I alpha 2 polypeptide, Collagen Of Skin Tendon And Bone, Collagen Type 1, Collagen type I alpha 1, Collagen type I alpha 2, OI4, Osteogenesis Imperfecta Type IV, Pro alpha 1(I) collagen, Type I procollagen, CO1A1_HUMAN.

Gene ID: 1277

UniProt: P02452