POLE antibody (AA 101-200) (HRP)

Catalog No. ABIN2178567

Product Details anti-POLE Antibody (HRP)

Target: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLE antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNA Polymerase epsilon subunit 2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for POLE

Target: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Alternative Name: DNA polymerase epsilon (POLE Products)

Synonyms: CRCS12 antibody, FILS antibody, POLE1 antibody, DPE2 antibody, DNA polymerase epsilon, catalytic subunit antibody, polymerase (DNA directed), epsilon antibody, DNA polymerase epsilon 2, accessory subunit antibody, polymerase (DNA directed), epsilon 2 (p59 subunit) antibody, POLE antibody, Pole antibody, POLE2 antibody, Pole2 antibody

Background:

Synonyms: DPE2, DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B, POLE2

Background: Participates in DNA repair and in chromosomal DNA replication.

Gene ID: 5427

UniProt: P56282

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA