Caspase 8 antibody

Catalog No. ABIN219257

The Mouse Monoclonal anti-Caspase 8 antibody is suitable to detect Caspase 8 in samples from Human. It has been validated for WB and IP.

Quick Overview for Caspase 8 antibody (ABIN219257)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Caspase 8 Antibody

Specificity: Recognizes Caspase 8 (FLICE). Species cross-reactivity: human.

Purification: Protein G purified

Immunogen: Recombinant full length human Caspase 8 protein.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: IP, WB

Usage: Immunoprecipitation (Denatured verified) (Use Protein G) (Ab 2 μg/mg protein lysate). Western Blot (Ab 2-4 μg/mL for 2hrs at RT).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades