AKT1 antibody (pSer473) (PE)

Catalog No. ABIN2198392

This Rabbit Monoclonal antibody specifically detects AKT1 in FACS. It exhibits reactivity toward Human.

Quick Overview for AKT1 antibody (pSer473) (PE) (ABIN2198392)

Target: AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This AKT1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 11C1015

Product Details anti-AKT1 Antibody (PE)

Binding Specificity: pSer473

Cross-Reactivity: Cow (Bovine), Caenorhabditis elegans (C. elegans), Dog (Canine), Chicken, Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Xenopus laevis, Zebrafish (Danio rerio)

Cross-Reactivity (Details): Calculated cross reactivity: Bo Ce Ca Ch Hm Hu Mk Mo Po Rb Xe Ze

Characteristics: Akt, phosphorylated (Ser473) (AKT1, Proto-oncogene c-Akt, MGC99656, Protein Kinase B, PKB, PKB-alpha, PRKBA, RAC, RAC-alpha Serine/threonine-protein Kinase, RAC-PK-alpha) (PE)

Purification: Purified

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser473 of human Akt.

Isotype: IgG

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a liquid in PBS, pH 7.2, less than 0.09 % sodium azide, 2 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 4°C

Target Details for AKT1

Target: AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Alternative Name: Akt

UniProt: P31749

Pathways: PI3K-Akt Signaling, RTK Signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Water Deprivation, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGFR1 Specific Signals, VEGF Signaling, Warburg Effect