KIT antibody (pTyr719)

Catalog No. ABIN219903

The Rabbit Polyclonal anti-KIT antibody (ABIN219903) specifically detects KIT in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for KIT antibody (pTyr719) (ABIN219903)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KIT Antibody

Binding Specificity: pTyr719

Specificity: Recognizes endogenous levels of c-Kit protein only when phosphorylated at Tyr719. This antibody cross-reacts with tyrosine-phosphorylated PDGF receptor but does not cross-react with other tyrosine-phosphorylated family members. Species cross-reactivity: human. Species sequence homology: mouse.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Tyr719 of mouse c-Kit. (KLH).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, WB (1:1000)

Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1:1000.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: C-Kit / CD117

Background: Name/Gene ID: KIT
Subfamily: PDGF Receptor
Family: Protein Kinase

Synonyms: KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen

Gene ID: 3815

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity