Synaptophysin antibody

Catalog No. ABIN225010

Product Details anti-Synaptophysin Antibody

Target: Synaptophysin (SYP)

Reactivity: Human, Mouse, Rat, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Represents an excellent marker for several neuroendocrine, neuronal and adrenal tumors. Neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas. Neuroendocrine tumors of epithelial origin: Pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids, medullary carcinoma of thyroid. Polypeptide reacting: Mr 38000 transmembrane glycoprotein of presynaptic vesicles. Reactivities on Cultured Cell Lines (tested so far): Rat PC-12 cell line. Species cross-reactivity: Human, bovine, rat, mouse.

Purification: Protein A purified

Immunogen: Synaptophysin from presynaptic vesicles, prepared from bovine brain.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: IF, IHC, IHC-Fr, IHC-P, WB

Usage: Suitable for use in Western Blot, Immunofluorescence and Immunohistochemistry (frozen and paraffin-embedded tissue and cytological material, Do not use protease pretreatment). Immunohistochemistry: 1:50 with PBS,  pH 7.4, Incubation Time 1 hr at RT, extended with paraffin.

Comment:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: deionized water

Concentration: Lot specific

Buffer: Lyophilized.

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: SYP / Synaptophysin (SYP Products)

Synonyms: syp-B antibody, xsypii antibody, MGC86267 antibody, MRXSYP antibody, A230093K24Rik antibody, AI848995 antibody, Syn antibody, p38 antibody, Syp1 antibody, mrxsyp antibody, syp antibody, xsypi antibody, synaptophysin S homeolog antibody, synaptophysin antibody, synaptophysin L homeolog antibody, synaptophysin a antibody, syp.S antibody, SYP antibody, syp antibody, Syp antibody, syp.L antibody, sypa antibody

Background: Name/Gene ID: SYP

Synonyms: SYP, MRX, Synaptophysin, MRXSYP

Gene ID: 6855

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity