Integrin beta 2 antibody (Biotin)

Catalog No. ABIN226345

This Rat Monoclonal antibody specifically detects Integrin beta 2 in FACS, WB, IP, IHC, IHC (fro) and IHC (p). It exhibits reactivity toward Mouse.

Quick Overview for Integrin beta 2 antibody (Biotin) (ABIN226345)

Target: Integrin beta 2 (ITGB2)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Integrin beta 2 Antibody (Biotin)

Specificity: Recognizes common beta2 subunit (Mr 95kD) of the LFA-1 integrin complex.

Purification: Purified

Immunogen: Cell membrane lysates derived from mouse T cell lymphoma BW5147.

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: Flo, IHC, IHC-Fr, IHC-P, IP, WB

Usage: Suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Western Blot. Flow Cytometry: 1 μg/1 x10⁶. Immunohistochemistry: paraffin embedded and frozen sections. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: ITGB2 / MAC-1 / CD18

Background: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gene ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation