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c-MET antibody (pTyr1349)

This Rabbit Polyclonal antibody specifically detects c-MET in WB, ELISA and IP. It exhibits reactivity toward Human, Mouse and Monkey.
Catalog No. ABIN228895

Quick Overview for c-MET antibody (pTyr1349) (ABIN228895)

Target

See all c-MET (MET) Antibodies
c-MET (MET) (Met Proto-Oncogene (MET))

Reactivity

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Human, Mouse, Monkey

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This c-MET antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • Binding Specificity

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    pTyr1349

    Specificity

    Recognizes Met only when phosphorylated at Tyr1349. Does not cross-react with other tyrosine-phosphorylated proteins. Species cross-reactivity: human, mouse and monkey. Species sequence homology: rat-100 % .

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic phosphotyrosine corresponding aa residues surrounding Tyrosine 1349 of human Met (KLH coupled).

    Type of Immunogen: Hapten

    Isotype

    IgG
  • Application Notes

    Approved: ELISA, IP (1:50), WB (1:1000)

    Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:50.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, BSA, 50 % glycerol.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    c-MET (MET) (Met Proto-Oncogene (MET))

    Alternative Name

    c-Met

    Background

    Name/Gene ID: MET
    Subfamily: HGF Receptor/MET
    Family: Protein Kinase

    Synonyms: MET, AUTS9, C-Met, HGF/SF receptor, HGFR, Met kinase, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, HGF receptor, RCCP2, Tyrosine-protein kinase Met

    Gene ID

    4233

    UniProt

    P08581

    Pathways

    RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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