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Insulin Receptor antibody (pTyr972)

This anti-Insulin Receptor antibody is a Rabbit Polyclonal antibody detecting Insulin Receptor in WB. Suitable for Human, Mouse and Rat.
Catalog No. ABIN230370

Quick Overview for Insulin Receptor antibody (pTyr972) (ABIN230370)

Target

See all Insulin Receptor (INSR) Antibodies
Insulin Receptor (INSR)

Reactivity

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Human, Mouse, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Insulin Receptor antibody is un-conjugated

Application

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Western Blotting (WB)
  • Binding Specificity

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    pTyr972

    Specificity

    Recognizes phospho-IR ( -subunit) (Tyr972) at approximately 95 kD. Species cross-reactivity: Human and Mouse tested. Predicted to cross-react with Rat (100 % homologous), based on sequence homology.

    Purification

    Immunoaffinity purified

    Immunogen

    Peptide corresponding to amino acid region encompassing the human, mouse and rat phospho-phospho-IR (Tyr972).

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG
  • Application Notes

    Approved: WB (1:1000)

    Usage: Suitable for use in Western Blot. Western Blot: 1:1000.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS (without Mg2+, Ca2+),  pH 7.2, 1 mg/mL BSA (IgG, protease free), 0.05 % sodium azide, 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    Insulin Receptor (INSR)

    Alternative Name

    INSR / Insulin Receptor

    Background

    Name/Gene ID: INSR
    Subfamily: Insulin receptor
    Family: Protein Kinase

    Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

    Gene ID

    3643

    UniProt

    P06213

    Pathways

    NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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