Insulin Receptor antibody (pTyr972)
Quick Overview for Insulin Receptor antibody (pTyr972) (ABIN230370)
Target
See all Insulin Receptor (INSR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr972
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Specificity
- Recognizes phospho-IR ( -subunit) (Tyr972) at approximately 95 kD. Species cross-reactivity: Human and Mouse tested. Predicted to cross-react with Rat (100 % homologous), based on sequence homology.
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Purification
- Immunoaffinity purified
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Immunogen
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Peptide corresponding to amino acid region encompassing the human, mouse and rat phospho-phospho-IR (Tyr972).
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
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Approved: WB (1:1000)
Usage: Suitable for use in Western Blot. Western Blot: 1:1000. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.2, 1 mg/mL BSA (IgG, protease free), 0.05 % sodium azide, 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Insulin Receptor (INSR)
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Alternative Name
- INSR / Insulin Receptor
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Background
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Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase
Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen -
Gene ID
- 3643
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UniProt
- P06213
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Pathways
- NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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