GSK3 alpha antibody (pSer21)

Catalog No. ABIN233073

This anti-GSK3 alpha antibody is a Mouse Monoclonal antibody detecting GSK3 alpha in WB. Suitable for Human.

Quick Overview for GSK3 alpha antibody (pSer21) (ABIN233073)

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GSK3 alpha antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSK3 alpha Antibody

Binding Specificity: pSer21

Specificity: Detects endogenous levels of GSK-3 alpha only when phosphorylated at Ser21. Species cross-reactivity: Human, mouse, rat, monkey and zebra fish.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser21 of human GSK-3alpha.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG2b

Application Details

Application Notes: Approved: WB (1:2000)

Usage: Suitable for use in Western Blot. Western Blot: 1:2000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol, less than 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GSK3 alpha

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Alternative Name: GSK3A / GSK3 Alpha

Background: Name/Gene ID: GSK3A
Subfamily: GSK-3
Family: Protein Kinase

Synonyms: GSK3A, GSK-3 alpha, GSK3 alpha

Gene ID: 2931

UniProt: P49840

Pathways: PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect