CCDC106 antibody

Catalog No. ABIN2423069

Product Details anti-CCDC106 Antibody

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC106 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human CCDC106

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCDC106

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Alternative Name: CCDC106 (CCDC106 Products)

Synonyms: im:6909208 antibody, zgc:113396 antibody, HSU79303 antibody, ZNF581 antibody, BC018462 antibody, RGD1566222 antibody, coiled-coil domain containing 106b antibody, coiled-coil domain containing 106 antibody, ccdc106b antibody, CCDC106 antibody, Ccdc106 antibody

Background: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.