ACP6 antibody

Catalog No. ABIN2423735

Product Details anti-ACP6 Antibody

Target: ACP6 (Acid Phosphatase 6, Lysophosphatidic (ACP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACP6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human ACP6

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ACP6

Target: ACP6 (Acid Phosphatase 6, Lysophosphatidic (ACP6))

Alternative Name: ACP6 (ACP6 Products)

Synonyms: ACP6 antibody, im:7147584 antibody, zgc:172268 antibody, MGC146066 antibody, ACPL1 antibody, LPAP antibody, PACPL1 antibody, 5730559A09Rik antibody, AU022842 antibody, mPACPL1 antibody, acid phosphatase 6, lysophosphatidic antibody, acid phosphatase 6, lysophosphatidic S homeolog antibody, ACP6 antibody, acp6 antibody, acp6.S antibody, Acp6 antibody

Background: Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.