NPPB antibody

Catalog No. ABIN2425627

Product Details anti-NPPB Antibody

Target: NPPB (Natriuretic Peptides B (NPPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human NPPB

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:150

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NPPB

Target: NPPB (Natriuretic Peptides B (NPPB))

Alternative Name: NPPB (NPPB Products)

Synonyms: BNP1 antibody, NPPB antibody, BNP antibody, Bnf antibody, AA408272 antibody, natriuretic peptide B antibody, natriuretic peptide type B antibody, NPPB antibody, Nppb antibody

Background: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

NCBI Accession: NM_002521

Pathways: Hormone Activity