KCNH2 antibody

Catalog No. ABIN2426047

Product Details anti-KCNH2 Antibody

Target: KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human KCNH2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KCNH2

Target: KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))

Alternative Name: KCNH2 (KCNH2 Products)

Synonyms: ERG1 antibody, HERG antibody, HERG1 antibody, Kv11.1 antibody, LQT2 antibody, SQT1 antibody, erg antibody, KCNH2 antibody, ERG antibody, gp-erg antibody, cerg antibody, derg antibody, erg1 antibody, AI326795 antibody, LQT antibody, Lqt2 antibody, M-erg antibody, Merg1 antibody, merg1a antibody, merg1b antibody, potassium voltage-gated channel subfamily H member 2 antibody, potassium voltage-gated channel, subfamily H (eag-related), member 6a antibody, potassium voltage-gated channel, subfamily H (eag-related), member 2 antibody, potassium voltage-gated channel subfamily H member 6 antibody, KCNH2 antibody, kcnh6a antibody, Kcnh2 antibody, KCNH6 antibody

Background: This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.

Molecular Weight: Calculated MW: 90 kDa

NCBI Accession: NP_000229