NFASC antibody
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- Target See all NFASC Antibodies
- NFASC (Neurofascin (NFASC))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NFASC antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human NFASC
- Isotype
- IgG
- Top Product
- Discover our top product NFASC Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Handling Advice
- Avoid freeze / thaw cycles.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Store at -20°C (regular) and -80°C (long term).
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- Target
- NFASC (Neurofascin (NFASC))
- Alternative Name
- NFASC (NFASC Products)
- Synonyms
- sc:d0205 antibody, NF antibody, NRCAML antibody, AA387016 antibody, D430023G06Rik antibody, mKIAA0756 antibody, neurofascin antibody, neurofascin homolog (chicken) a antibody, NFASC antibody, nfasca antibody, Nfasc antibody
- Background
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This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.
Synonyms: NF, NRCAML - Pathways
- Cell-Cell Junction Organization
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