AGRN antibody

Catalog No. ABIN2426533

Product Details anti-AGRN Antibody

Target: AGRN (Agrin (AGRN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGRN antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human AGRN

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AGRN

Target: AGRN (Agrin (AGRN))

Alternative Name: AGRN (AGRN Products)

Synonyms: AGRIN antibody, agrn antibody, wu:fb57e07 antibody, Agrin antibody, nmf380 antibody, AGR antibody, HSPG antibody, agrin antibody, LOC465392 antibody, agrn antibody, AGRN antibody, Agrn antibody

Background: AGRIN,Agrin proteoglycan,AGRN,FLJ45064,OTTHUMP00000044043,This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found.

NCBI Accession: NP_940978

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development