FZD6 antibody (Frizzled Family Receptor 6)

Details for Product anti-FZD6 Antibody No. ABIN2427012, Supplier: Log in to see
Antigen
  • zgc:65879
  • zgc:77440
  • fz6
  • frz6
  • Xfrz6
  • frizzled6
  • frizzled-6
  • FZ-6
  • FZ6
  • HFZ6
  • NDNC10
  • Frizzled-6
  • Fz6
  • frizzled class receptor 6
  • frizzled class receptor 6 S homeolog
  • fzd6
  • fzd6.S
  • FZD6
  • Fzd6
Alternatives
anti-Human FZD6 antibody for Immunofluorescence
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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6
2
Clonality
Polyclonal
Conjugate
This FZD6 antibody is un-conjugated
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3
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1
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Application
Immunohistochemistry (IHC), ELISA
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34
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9
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Options
Supplier
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Immunogen Synthetic peptide of human FZD6
Isotype IgG
Purification Antigen affinity purification
Plasmids, Primers & others Plasmids, Primers & others FZD6 products on genomics-online (e.g. as negative or positive controls)
Alternative Name FZD6 (FZD6 Antibody Abstract)
Background This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Synonyms: FZ6, FZ-6, HFZ6, NDNC10
Pathways WNT Signaling, Tube Formation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Frizzled Family Receptor 6 (FZD6) antibody (ABIN2427012) Immunohistochemistry of Human gastric cancer using FZD6 Polyclonal Antibody at diluti...
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