CELSR2 antibody

Catalog No. ABIN2427023

Product Details anti-CELSR2 Antibody

Target: CELSR2 (Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELSR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human CELSR2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CELSR2

Target: CELSR2 (Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2))

Alternative Name: CELSR2 (CELSR2 Products)

Synonyms: CDHF10 antibody, EGFL2 antibody, Flamingo1 antibody, MEGF3 antibody, Megf3 antibody, flamingo antibody, mKIAA0279 antibody, mfmi1 antibody, cadherin EGF LAG seven-pass G-type receptor 2 antibody, cadherin, EGF LAG seven-pass G-type receptor 2 antibody, CELSR2 antibody, Celsr2 antibody

Background: The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins, a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

NCBI Accession: NP_001399