ECE2 antibody

Catalog No. ABIN2428066

Product Details anti-ECE2 Antibody

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human ECE2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ECE2

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Alternative Name: ECE2 (ECE2 Products)

Synonyms: ECE2 antibody, 1810009K13Rik antibody, 6330509A19Rik antibody, 9630025D12Rik antibody, BB127715 antibody, endothelin converting enzyme 2 antibody, endothelin-converting enzyme 2 antibody, ECE2 antibody, LOC702851 antibody, ece2 antibody, LOC100543478 antibody, Ece2 antibody

Background: Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling