CCR2 antibody

Catalog No. ABIN2431139

Product Details anti-CCR2 Antibody

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human CCR2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Alternative Name: CD192 (CCR2 Products)

Synonyms: CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody

Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

Molecular Weight: Calculated MW: 42 kDa

NCBI Accession: NP_001116513

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process