GFRA3 antibody

Catalog No. ABIN2431443

Product Details anti-GFRA3 Antibody

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human GFRA3

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:150

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GFRA3

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Alternative Name: GFRA3 (GFRA3 Products)

Synonyms: GFRA3 antibody, GFRalpha3 antibody, Y15110 antibody, GDNF family receptor alpha 3 antibody, glial cell line derived neurotrophic factor family receptor alpha 3 antibody, Gfra3 antibody, GFRA3 antibody

Background: GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

NCBI Accession: NP_001487