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Cdk11A/B antibody

Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2432821
  • Target
    Cdk11A/B
    Reactivity
    Human
    Host
    • 2
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 2
    Un-conjugated
    Application
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human CDK11A/CDK11B
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Cdk11A/B
    Background
    Cyclin-dependent kinases (CDKs)are a family ofproteinkinasesfirst discovered for their role in regulating thecell cycle. They are also involved in regulatingtranscription, mRNA processing, and the differentiation of nerve cells. They are present in all knowneukaryotes, and their regulatory function in thecell cyclehas been evolutionarily conserved. CDKs are relatively small proteins, witHuman, Mouseolecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity, only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.
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