PAX7 antibody

Catalog No. ABIN2457950

Product Details anti-PAX7 Antibody

Target: PAX7 (Paired Box 7 (PAX7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX7.

Application Details

Application Notes: PAX7 antibody can be used for detection of PAX7 by ELISA at 1:12500. PAX7 antibody can be used for detection of PAX7 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAX7 antibody at -20 °C.

Target Details for PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Alternative Name: PAX7 (PAX7 Products)

Synonyms: PAX7 antibody, HUP1 antibody, PAX7B antibody, RMS2 antibody, pax-7 antibody, PAX-7 antibody, RGD1564360 antibody, Pax-7 antibody, pax7 antibody, pax7c antibody, pax7d antibody, pax7e antibody, paired box 7 antibody, paired box protein Pax-7 antibody, paired box 7 L homeolog antibody, paired box 7a antibody, PAX7 antibody, pax7.L antibody, LOC536229 antibody, Pax7 antibody, pax7a antibody

Background: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown. This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Molecular Weight: 57 kDa

Gene ID: 5081

NCBI Accession: NP_002575

UniProt: P23759