HTR3C antibody

Catalog No. ABIN2458143

Product Details anti-HTR3C Antibody

Target: HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3C.

Application Details

Application Notes: HTR3C antibody can be used for detection of HTR3C by ELISA at 1:62500. HTR3C antibody can be used for detection of HTR3C by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HTR3C antibody at -20 °C.

Target Details for HTR3C

Target: HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))

Alternative Name: HTR3C (HTR3C Products)

Synonyms: 5-hydroxytryptamine receptor 3C antibody, 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic antibody, HTR3C antibody, LOC100066962 antibody, LOC607416 antibody, LOC706232 antibody

Background: HTR3C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.

Molecular Weight: 50 kDa

Gene ID: 170572

NCBI Accession: NP_570126

UniProt: Q8WXA8