GJC2 antibody

Catalog No. ABIN2458256

Product Details anti-GJC2 Antibody

Target: GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJC2.

Application Details

Application Notes: GJC2 antibody can be used for detection of GJC2 by ELISA at 1:312500. GJC2 antibody can be used for detection of GJC2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GJC2 antibody at -20 °C.

Target Details for GJC2

Target: GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))

Alternative Name: GJC2 (GJC2 Products)

Synonyms: GJA12 antibody, cx47 antibody, gja12 antibody, cx46.6 antibody, pmldar antibody, MGC146420 antibody, B230382L12Rik antibody, Cx47 antibody, Gja12 antibody, CX46.6 antibody, HLD2 antibody, LMPH1C antibody, PMLDAR antibody, SPG44 antibody, gap junction protein gamma 2 antibody, si:dkey-91f15.1 antibody, gap junction protein, gamma 2 antibody, GJC2 antibody, gjc2 antibody, si:dkey-91f15.1 antibody, Gjc2 antibody

Background: GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

Molecular Weight: 47 kDa

Gene ID: 57165

NCBI Accession: NP_065168

UniProt: Q5T442