NR1H3 antibody
-
- Target See all NR1H3 Antibodies
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This NR1H3 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1H3.
- Top Product
- Discover our top product NR1H3 Primary Antibody
-
-
- Application Notes
- NR1H3 antibody can be used for detection of NR1H3 by ELISA at 1:62500. NR1H3 antibody can be used for detection of NR1H3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR1H3 antibody at -20 °C.
-
- Target
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Alternative Name
- NR1H3 (NR1H3 Products)
- Synonyms
- NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
- Background
- Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
- Molecular Weight
- 50 kDa
- Gene ID
- 10062
- NCBI Accession
- NP_005684
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
-