HNRNPR antibody

Catalog No. ABIN2458517

Product Details anti-HNRNPR Antibody

Target: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HNRNPR.

Application Details

Application Notes: HNRNPR antibody can be used for detection of HNRNPR by ELISA at 1:62500. HNRNPR antibody can be used for detection of HNRNPR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HNRNPR antibody at -20 °C.

Target Details for HNRNPR

Target: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Alternative Name: HNRNPR (HNRNPR Products)

Synonyms: hnrpr antibody, wu:fb97a09 antibody, wu:fe01h03 antibody, zgc:56523 antibody, HNRPR antibody, hnRNP R antibody, hnRNP-R antibody, 2610003J05Rik antibody, 2610528B01Rik antibody, Hnrpr antibody, heterogeneous nuclear ribonucleoprotein R antibody, hnrnpr antibody, HNRNPR antibody, Hnrnpr antibody

Background: HNRNPR belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 71 kDa

Gene ID: 10236

NCBI Accession: NP_005817

UniProt: O43390