A1CF antibody
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- Target See all A1CF Antibodies
- A1CF (APOBEC1 Complementation Factor (A1CF))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This A1CF antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A1CF.
- Top Product
- Discover our top product A1CF Primary Antibody
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- Application Notes
- A1CF antibody can be used for detection of A1CF by ELISA at 1:1562500. A1CF antibody can be used for detection of A1CF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store A1CF antibody at -20 °C.
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- Target
- A1CF (APOBEC1 Complementation Factor (A1CF))
- Alternative Name
- A1CF (A1CF Products)
- Synonyms
- ACF antibody, ACF64 antibody, ACF65 antibody, APOBEC1CF antibody, ASP antibody, 1810073H04Rik antibody, Acf antibody, A1cft antibody, Apobec-1 antibody, acf antibody, acf64 antibody, acf65 antibody, apobec1cf antibody, asp antibody, A1CF antibody, APOBEC1 complementation factor antibody, apobec1 complementation factor antibody, APOBEC1 complementation factor L homeolog antibody, A1CF antibody, A1cf antibody, a1cf antibody, a1cf.L antibody
- Background
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
- Molecular Weight
- 65 kDa
- Gene ID
- 29974
- NCBI Accession
- NP_620311
- UniProt
- Q9NQ94
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