TGM1 antibody

Catalog No. ABIN2458600

Product Details anti-TGM1 Antibody

Target: TGM1 (Transglutaminase 1, Keratinocyte (TGM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TGM1.

Application Details

Application Notes: TGM1 antibody can be used for detection of TGM1 by ELISA at 1:1562500. TGM1 antibody can be used for detection of TGM1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TGM1 antibody at -20 °C.

Target Details for TGM1

Target: TGM1 (Transglutaminase 1, Keratinocyte (TGM1))

Alternative Name: TGM1 (TGM1 Products)

Synonyms: TGM1 antibody, ARCI1 antibody, ICR2 antibody, KTG antibody, LI antibody, LI1 antibody, TGASE antibody, TGK antibody, 2310004J08Rik antibody, Tgase1 antibody, transglutaminase 1 antibody, transglutaminase 1, K polypeptide antibody, Tgm1 antibody, TGM1 antibody

Background: TGM1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 90 kDa

Gene ID: 7051

NCBI Accession: NP_000350

UniProt: P22735