CYP4B1
Reactivity: Human
WB, IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
CYP4B1 antibody can be used for detection of CYP4B1 by ELISA at 1:312500. CYP4B1 antibody can be used for detection of CYP4B1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice
As with any antibody avoid repeat freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
For short periods of storage (days) store at 4 °C. For longer periods of storage, store CYP4B1 antibody at -20 °C.
Target
CYP4B1
(Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 (CYP4B1))
CYPIVB1 antibody, P-450HP antibody, cytochrome P450, family 4, subfamily B, polypeptide 1 antibody, CYP4B1-like isozyme short form antibody, cytochrome P450, family 4, subfamily B, polypeptide 1 L homeolog antibody, cytochrome P450 family 4 subfamily B member 1 antibody, cytochrome P450, family 4, subfamily b, polypeptide 1 antibody, cytochrome P450 family 4 subfamily B member 1 L homeolog antibody, CYP4B1 antibody, cyp4b1.L antibody, cyp4b1 antibody, Cyp4b1 antibody, cyp4b1.2.L antibody
Background
CYP4B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.