FBXW2 antibody
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- Target See all FBXW2 Antibodies
- FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXW2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXW2.
- Top Product
- Discover our top product FBXW2 Primary Antibody
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- Application Notes
- FBXW2 antibody can be used for detection of FBXW2 by ELISA at 1:1562500. FBXW2 antibody can be used for detection of FBXW2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBXW2 antibody at -20 °C.
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- Target
- FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
- Alternative Name
- FBXW2 (FBXW2 Products)
- Synonyms
- FBXW2 antibody, md6 antibody, fbw2 antibody, fwd2 antibody, MGC53244 antibody, FBW2 antibody, Fwd2 antibody, Md6 antibody, wu:fc72f10 antibody, zgc:110365 antibody, 2700071L08Rik antibody, MD6 antibody, F-box and WD repeat domain containing 2 antibody, F-box and WD repeat domain containing 2 L homeolog antibody, F-box and WD-40 domain protein 2 antibody, FBXW2 antibody, fbxw2 antibody, Fbxw2 antibody, fbxw2.L antibody
- Background
- F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. FBXW2 is the second identified member of the F-box family and contains multiple WD-40 repeats.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
- Molecular Weight
- 51 kDa
- Gene ID
- 26190
- NCBI Accession
- NP_036296
- UniProt
- Q9UKT8
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