BAAT antibody

Catalog No. ABIN2458950

Product Details anti-BAAT Antibody

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAAT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BAAT.

Application Details

Application Notes: BAAT antibody can be used for detection of BAAT by ELISA at 1:62500. BAAT antibody can be used for detection of BAAT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store BAAT antibody at -20 °C.

Target Details for BAAT

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Alternative Name: BAAT (BAAT Products)

Synonyms: BACAT antibody, BAT antibody, AI118337 antibody, AI158864 antibody, kan-1 antibody, BAAT antibody, bile acid-CoA:amino acid N-acyltransferase antibody, Bile acid-CoA:amino acid N-acyltransferase antibody, bile acid-Coenzyme A: amino acid N-acyltransferase antibody, bile acid CoA:amino acid N-acyltransferase antibody, BAAT antibody, RPIC_RS10270 antibody, Bcav_2277 antibody, Rpic12D_1765 antibody, Baat antibody, LOC481635 antibody, LOC100054567 antibody, LOC786798 antibody

Background: BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 46 kDa

Gene ID: 570

NCBI Accession: NP_001692

UniProt: Q14032