CENPM
Reactivity: Human
WB, IP
Host: Rat
Monoclonal
23F6
unconjugated
Application Notes
CENPM antibody can be used for detection of CENPM by ELISA at 1:312500. CENPM antibody can be used for detection of CENPM by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice
As with any antibody avoid repeat freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
For short periods of storage (days) store at 4 °C. For longer periods of storage, store CENPM antibody at -20 °C.
C22orf18 antibody, CENP-M antibody, PANE1 antibody, bK250D10.2 antibody, 2610019I03Rik antibody, AI853711 antibody, Pane1 antibody, RGD1307309 antibody, centromere protein M antibody, centromere protein M L homeolog antibody, Centromere protein M antibody, centromere protein M pseudogene antibody, CENPM antibody, Cenpm antibody, cenpm antibody, cenpm.L antibody, LOC100353362 antibody
Background
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).