INTS4 antibody

Catalog No. ABIN2459491

Product Details anti-INTS4 Antibody

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human INTS4.

Application Details

Application Notes: INTS4 antibody can be used for detection of INTS4 by ELISA at 1:12500. INTS4 antibody can be used for detection of INTS4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store INTS4 antibody at -20 °C.

Target Details for INTS4

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Alternative Name: INTS4 (INTS4 Products)

Synonyms: DDBDRAFT_0187061 antibody, DDBDRAFT_0234080 antibody, DDB_0187061 antibody, DDB_0234080 antibody, INT4 antibody, MST093 antibody, 2610034N24Rik antibody, AA692684 antibody, AW493223 antibody, RGD1305036 antibody, integrator complex subunit 4 antibody, HEAT repeat-containing protein antibody, ARM repeat superfamily protein antibody, integrator complex subunit 4 L homeolog antibody, CpipJ_CPIJ015422 antibody, ints4 antibody, NAEGRDRAFT_79682 antibody, INTS4 antibody, SIEL antibody, Ints4 antibody, ints4.L antibody

Background: INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).

Molecular Weight: 108 kDa

Gene ID: 92105

NCBI Accession: NP_291025

UniProt: Q96HW7

Pathways: SARS-CoV-2 Protein Interactome