TFAP2B antibody

Catalog No. ABIN2459994

Product Details anti-TFAP2B Antibody

Target: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFAP2B.

Application Details

Application Notes: TFAP2B antibody can be used for detection of TFAP2B by ELISA at 1:62500. TFAP2B antibody can be used for detection of TFAP2B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TFAP2B antibody at -20 °C.

Target Details for TFAP2B

Target: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Alternative Name: TFAP2B (TFAP2B Products)

Synonyms: TFAP2B antibody, AP-2B antibody, Tcfap2b antibody, AP2 antibody, si:dkey-5e16.1 antibody, zgc:110163 antibody, AP-1beta1 antibody, AP-2beta antibody, AP-beta1 antibody, AP1beta1 antibody, AP2beta2 antibody, BAD1 antibody, BAP antibody, Beta-adaptin antibody, CG12532 antibody, Dmel\\CG12532 antibody, bap antibody, beta1/2 antibody, cg12532 antibody, AI606113 antibody, AP-2(beta) antibody, E130018K07Rik antibody, AP2-B antibody, ap-2b antibody, ap2-b antibody, tfap2beta antibody, transcription factor AP-2 beta antibody, beta-adaptin antibody, putative beta-adaptin antibody, Adaptor Protein complex 1/2, beta subunit antibody, transcription factor AP-2 beta L homeolog antibody, TFAP2B antibody, Tfap2b antibody, tfap2b antibody, Tc00.1047053509799.10 antibody, Tc00.1047053506247.200 antibody, LINJ_36_7080 antibody, LBRM_35_7120 antibody, LMJF_36_6770 antibody, Tcfap2b antibody, AP-1-2beta antibody, Tsp_09571 antibody, tfap2b.L antibody

Background: TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes. This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-144 AU141084.1 1-144 145-1684 BC037225.1 1-1540 1685-5370 AL049693.16 11928-15613 5371-5770 BU738725.1 18-417 c

Molecular Weight: 50 kDa

Gene ID: 7021

NCBI Accession: NP_003212

UniProt: Q92481

Pathways: Carbohydrate Homeostasis, Synaptic Membrane